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Rabbit anti-PVRIG Recombinant Monoclonal Antibody [BLR296L]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PVRIG

Reactivity:

Human

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR296L

Format:

Whole IgG

Immunogen:

between 200 and 250

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

PVRIG, aka CD112R, is a cell surface receptor for NECTIN2 that acts as a coinhibitory receptor suppressing T-cell receptor-mediated signals. Following interaction with NECTIN2, PVRIG inhibits T-cell proliferation. PVRIG also competes with CD226 for NECTIN2-binding. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6DKI7].

79037

PVRIG

PVR related immunoglobulin domain containing

Q6DKI7

Transmembrane protein PVRIG

Alternate Names

C7orf15;CD112 receptor;CD112R;nectin-2 receptor;poliovirus receptor related immunoglobulin domain containing;poliovirus receptor-related immunoglobulin domain-containing protein;transmembrane protein PVRIG

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).