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Rabbit anti-Rad50 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Rad50

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 700 and 750

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Presumed Reactivity

Dog,

Rabbit,

Bovine,

Monkey

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.

10111

RAD50

RAD50 double strand break repair protein

Q92878

DNA repair protein RAD50

Alternate Names

DNA repair protein RAD50; hRad50; NBSLD; RAD50 homolog, double strand break repair protein; RAD502

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.