Rabbit anti-TIF1 Alpha/TRIM24 IHC Antibody Affinity Purified
Catalog #
TIF1 Alpha/TRIM24
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 700 and 750
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Guinea Pig,
Horse,
Dog,
Rabbit,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.
Alternate Names
E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; TIF1-alpha; transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; Tripartite motif-containing protein 24
Applications
