Rabbit anti-NCOA5/CIA IHC Antibody Affinity Purified
Catalog #
NCOA5/CIA
Human
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 525 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Monkey
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to NCOA5/CIA immobilized on solid support.
The epitope recognized by IHC-00476 maps to a region between residue 525 and the C-terminus (residue 579) of human Nuclear Receptor Coactivator 5 (Coactivator Independent of AF-2) using the numbering given in entry NP_066018.1 (GeneID 57727).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to NCOA5/CIA immobilized on solid support.
The epitope recognized by IHC-00476-T maps to a region between residue 525 and the C-terminus (residue 579) of human Nuclear Receptor Coactivator 5 (Coactivator Independent of AF-2) using the numbering given in entry NP_066018.1 (GeneID 57727).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
NCOA5 (Nuclear Receptor Coactivator 5), also known as CIA (Coactivator Independent of AF-2 function), has been shown interact exclusively with estrogen receptor alpha (ERalpha) and beta (ERbeta) to function as a coactivator and enhance transcriptional activation by ER. NCOA5 has also been demonstrated to function as a corepressor of MYC/c-myc in response to 17-beta estradiol.
Alternate Names
bA465L10.6; CIA; coactivator independent of AF-2; NCoA-5; nuclear receptor coactivator 5
Applications