Bethyl Laboratories® Rabbit anti-PABP4 IHC Antibody, Affinity Purified - 100 µl (50+ slides)
Catalog #
PABP4
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 525 and 575
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Guinea Pig,
Horse,
Dog,
Pig,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
PABP4 (poly(A)-binding protein 4), also known as iPABP (inducible poly(A)-binding protein) was originally identified in a search for activation-induced genes in T-cells. It is one of five poly(A)-binding proteins encoded by independent genes whose products play roles in various aspects of mRNA processing. The PABP genes encode one nuclear and four cytoplasmic PABP proteins. PABP2/PABP (PABPN1) is the observed nuclear PABP. The cytoplasmic PABPs include PABP1 (PABPC1), PABP3 (PABPC3), PABP4/iPABP (PABPC4), and x-linked PABP5 (PABPC5). The cytoplasmic PABPs bear four RNA-recognition motifs (RRMs) that participate in binding poly (A). In T-cells, PABP4 is proposed to play a role in stabilizing labile mRNA.
Alternate Names
activated-platelet protein 1; APP1; APP-1; inducible poly(A)-binding protein; iPABP; PABP4; PABP-4; poly(A) binding protein, cytoplasmic 4 (inducible form); poly(A)-binding protein 4; polyadenylate-binding protein 4
Applications
