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Rabbit anti-PDZ-GEF1 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PDZ-GEF1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 975 and 1025

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Guinea_pig,

Mouse,

Horse,

Dog,

Pig,

Rabbit,

Monkey

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

PDZ-GEF1 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity.

9693

RAPGEF2

Rap guanine nucleotide exchange factor 2

Q9Y4G8

Rap guanine nucleotide exchange factor 2

Alternate Names

CNrasGEF; cyclic nucleotide ras GEF; neural RAP guanine nucleotide exchange protein; nRap GEP; NRAPGEP; PDZ domain containing guanine nucleotide exchange factor (GEF) 1; PDZ domain-containing guanine nucleotide exchange factor 1; PDZGEF1; PDZ-GEF1; RA(Ras/Rap1A-associating)-GEF; RAGEF; RA-GEF; RA-GEF-1; Rap guanine nucleotide exchange factor (GEF) 2; rap guanine nucleotide exchange factor 2; Rap-GEP; ras/Rap1-associating GEF-1

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer or tris-EDTA pH9.0 buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.