/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-ARAP3 Antibody
NEW!
Primary Antibodies  

Rabbit anti-ARAP3 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

ARAP3

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1200 and 1250

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


Request Formulation Change

Fortis Guarantee

Guaranteed Performance, Excellent Service!
Learn more
Additional Product Information

ARAP3 is a phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. It is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. It can also be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. ARAP3 acts on ARF6, RAC1, RHOA and CDC42. ARAP3 plays a role in the internalization of anthrax toxin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WWN8].

64411

ARAP3

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

Q8WWN8

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

Alternate Names

Arf and Rho GAP adapter protein 3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; centaurin-delta-3; CENTD3; Cnt-d3; DRAG1; phosphoinositide binding protein; PtdIns(3,4,5)P3-binding protein

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.