Rabbit anti-FBXO31 Antibody Affinity Purified
Catalog #
FBXO31
Human
,Mouse
WB
Rabbit
Polyclonal
Whole IgG
Between 489 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
FBXO31 (F-box only protein 31) is a member of the F-box family of proteins and a component of the SCF (SKP1-cullin-F-box) protein ligase complex. FBXO31 is a candidate tumor suppressor protein that displays loss of heterozygosity in breast, ovarian, hepatocellular, and prostate cancers. In the DNA damage response FBXO31 has been found to mediate the degradation of cyclin D1 via a proteasome-directed pathway.
Alternate Names
F-box only protein 31; FBX14; Fbx31; FBXO14; MRT45; pp2386; putative breast cancer tumor-suppressor; SCF ubiquitin ligase specificity factor
Applications